Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544004 | 0.87 | HRH3 (0.41) | L3MBTL1ALDH1A1CYP1A2GRM5HRH3 | |
| SCHEMBL6544010 | 0.87 | HRH3 (0.41) | L3MBTL1ALDH1A1CYP1A2GRM5HRH3 | |
| SCHEMBL28309390 | 0.78 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1CYP1A2GRM5USP2 | |
| SCHEMBL5320056 | 0.72 | ALDH1A1 (0.52) | ALDH1A1USP2NPSR1TAAR1ALOX15 | |
| SCHEMBL29830938 | 0.72 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1HRH3HRH4HRH1 | |
| SCHEMBL41191 | 0.72 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1HRH3HRH4HRH1 | |
| SCHEMBL1399903 | 0.72 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL6806443 | 0.71 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL111084 | 0.71 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL112394 | 0.71 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499558-B | Asymmetric reduction method of chiral spiro-bis-boron catalytic substituted pyridine and application thereof | 南开大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-111499558-A | Asymmetric reduction method for chiral spiro-bisboron catalyzed substituted pyridine and application thereof | 南开大学 | 2020-08-07 | — | — | CN | disclosed |