Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544004 | 1.00 | HRH3 (0.41) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL28444367 | 0.87 | L3MBTL1 (0.45) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL6543931 | 0.76 | ALDH1A1 (0.40) | ALDH1A1ALOX15L3MBTL1KMT2AMEN1 | |
| SCHEMBL6399434 | 0.70 | ALDH1A1 (0.33) | HRH3ALDH1A1LMNATAAR1ALOX15 | |
| SCHEMBL41191 | 0.70 | L3MBTL1 (0.59) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL29830938 | 0.70 | L3MBTL1 (0.59) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| SCHEMBL4938201 | 0.68 | L3MBTL1 (0.57) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| Ammonia Solution, Strong SCHEMBL6176560 | 0.68 | L3MBTL1 (0.57) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| Bromide SCHEMBL6114859 | 0.68 | L3MBTL1 (0.57) | HRH3HRH1ALDH1A1LMNATAAR1 | |
| Hydrochloric Acid SCHEMBL10884973 | 0.68 | L3MBTL1 (0.57) | HRH3HRH1ALDH1A1LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375465-A9 | CYCLOOCTANONE DERIVATIVE AND CYCLODECANONE DERIVATIVE, AND USE THEREOF | Eisai Co., Ltd. (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-1375479-A1 | PYRROLIDINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Eisai Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |