Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30271589 | 0.79 | HPGD (0.55) | HPGDLMNAKDM4EALDH1A1TDP1 | |
| SCHEMBL31013354 | 0.78 | RAB9A (0.48) | HPGDALDH1A1TDP1SMN1; SMN2MAPT | |
| SCHEMBL3205838 | 0.78 | RAB9A (0.55) | HPGDLMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL28075523 | 0.77 | HPGD (0.72) | HPGDHSD17B10ALOX15LMNATSHR | |
| Azobenzene SCHEMBL28075526 | 0.76 | ALDH1A1 (0.75) | HPGDHSD17B10ALOX15LMNATSHR | |
| SCHEMBL29020028 | 0.72 | MYC (0.56) | HPGDHSD17B10LMNATSHRKDM4E | |
| SCHEMBL28233495 | 0.72 | MAPT (0.47) | HPGDLMNAKDM4EALDH1A1TDP1 | |
| SCHEMBL29525350 | 0.71 | LMNA (0.68) | HPGDHSD17B10ALOX15LMNATSHR | |
| SCHEMBL3908136 | 0.71 | LMNA (0.68) | HPGDHSD17B10ALOX15LMNATSHR | |
| SCHEMBL10203414 | 0.71 | LMNA (0.68) | HPGDHSD17B10ALOX15LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088784-A | Synthesis method of mesalamine | 广州市桐晖药业有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116003274-A | Method for synthesizing catalyst-free 5-aminosalicylic acid | 浙江华贝药业有限责任公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-116003274-A | Method for synthesizing catalyst-free 5-aminosalicylic acid | 浙江华贝药业有限责任公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-114605277-B | Synthesis method of mesalazine | 宁波怡和医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-114605277-A | Synthesis method of mesalazine | 宁波怡和医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-111533663-B | Method for synthesizing mesalazine | 常州工程职业技术学院 | 2022-03-08 | — | — | CN | disclosed |
| CN-111533663-A | Method for synthesizing mesalazine | 常州工程职业技术学院 | 2020-08-14 | — | — | CN | disclosed |