Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 11/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26397406 | 1.00 | FKBP1A (0.53) | FKBP1AKLK7HSD11B1ALDH1A1CYP3A4 | |
| SCHEMBL20811255 | 1.00 | FKBP1A (0.53) | FKBP1AKLK7HSD11B1ALDH1A1CYP3A4 | |
| SCHEMBL14348059 | 0.88 | ALDH1A1 (0.52) | HSD11B1ALDH1A1CYP3A4TSHR | |
| SCHEMBL2070692 | 0.88 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL14348055 | 0.88 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL20791017 | 0.87 | FKBP1A (0.55) | FKBP1AALDH1A1CYP3A4TSHR | |
| SCHEMBL20791015 | 0.87 | FKBP1A (0.55) | FKBP1AALDH1A1CYP3A4TSHR | |
| SCHEMBL9037346 | 0.86 | KLK7 (0.54) | FKBP1AKLK7ALDH1A1CYP3A4 | |
| SCHEMBL7307432 | 0.86 | KLK7 (0.61) | FKBP1AKLK7 | |
| SCHEMBL9609458 | 0.86 | KLK7 (0.61) | FKBP1AKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601798-B | Bisamide sarcomere activating compounds and uses thereof | 美国安进公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-111601798-A | Bisamide sarcomere activating compound and use thereof | 美国安进公司 | 2020-08-28 | — | — | CN | disclosed |