Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030323 | 0.89 | MTNR1A (0.64) | MTNR1AMTNR1BMEN1KMT2AMAPT | |
| SCHEMBL498040 | 0.86 | CHRNB2 (0.56) | CHRNB2CHRNA7CHRNA4NPC1MTNR1A | |
| SCHEMBL29506986 | 0.86 | CHRNB2 (0.56) | CHRNB2CHRNA7CHRNA4NPC1MTNR1A | |
| SCHEMBL15323543 | 0.85 | HTR2C (0.58) | NPC1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL20931043 | 0.84 | HPGD (0.56) | NPC1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL30517178 | 0.83 | CHRNB2 (0.58) | CHRNB2CHRNA7CHRNA4NPC1MTNR1A | |
| SCHEMBL7423854 | 0.83 | NPC1 (0.76) | NPC1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL24448409 | 0.81 | CDK2 (0.50) | NPC1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL4605682 | 0.81 | MTNR1A (0.55) | NPC1MTNR1AMTNR1BMEN1KMT2A | |
| Methyl 3-(3-Indolylmethyl)Propanoate SCHEMBL290808 | 0.80 | MAPT (0.71) | MEN1KMT2AMAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499591-A | ROR gamma modulators | 山东轩竹医药科技有限公司 | 2020-08-07 | — | — | CN | disclosed |