Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | GOT1 | P17174 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14487672 | 0.87 | MEN1 (0.50) | CDK2TRPV1NPC1MEN1KMT2A | |
| SCHEMBL15323543 | 0.82 | HTR2C (0.58) | TRPV1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL28445347 | 0.81 | CHRNB2 (0.60) | CDK2NPC1MEN1KMT2AMTNR1A | |
| SCHEMBL20931043 | 0.81 | HPGD (0.56) | NPC1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7423854 | 0.80 | NPC1 (0.76) | CDK2NPC1MEN1KMT2AMTNR1A | |
| SCHEMBL9491691 | 0.78 | PPARA (0.47) | KMT2AALDH1A1CYP1A2MAPT | |
| SCHEMBL13715393 | 0.78 | TBXAS1 (0.53) | CDK2TRPV1MEN1KMT2AALDH1A1 | |
| SCHEMBL12327114 | 0.78 | TBXAS1 (0.56) | CDK2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL13049135 | 0.78 | CHRNB2 (0.63) | CDK2TRPV1MEN1KMT2AALDH1A1 | |
| SCHEMBL4605682 | 0.78 | MTNR1A (0.55) | NPC1MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001279-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | Enanta Pharmaceuticals, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |