Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL38666345 | 0.84 | ADRA2A (0.42) | NISCHADRA2A | |
| SCHEMBL8367405 | 0.77 | — | — | |
| SCHEMBL20924189 | 0.70 | NISCH (0.56) | NISCHADRA2AALDH1A1HPGD | |
| SCHEMBL22400184 | 0.68 | NISCH (0.36) | NISCHADRA2A | |
| SCHEMBL855414 | 0.68 | NISCH (0.36) | NISCHADRA2A | |
| SCHEMBL2360679 | 0.67 | — | — | |
| SCHEMBL11562330 | 0.65 | ALDH1A1 (0.34) | ALDH1A1PKMHPGD | |
| SCHEMBL11135927 | 0.64 | ALDH1A1 (0.33) | ALDH1A1PKMHPGD | |
| SCHEMBL10616810 | 0.64 | ALDH1A1 (0.33) | ALDH1A1PKMHPGD | |
| SCHEMBL11463750 | 0.64 | ALDH1A1 (0.33) | ALDH1A1PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258334-B2 | N-alkanoyl-N,N′,N′-alkylenediamine trialkanoic acid esters | IRIX PHARMACEUTICALS, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258334-B2 | N-alkanoyl-N,N′,N′-alkylenediamine trialkanoic acid esters | IRIX PHARMACEUTICALS, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258334-B2 | N-alkanoyl-N,N′,N′-alkylenediamine trialkanoic acid esters | IRIX PHARMACEUTICALS, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-20100130770-A1 | N-ALKANOYL-N,N',N'-ALKYLENEDIAMINE TRIALKANOIC ACID ESTERS | IRIX PHARMACEUTICALS | 2010-05-27 | — | — | US | disclosed |
| US-20100130770-A1 | N-ALKANOYL-N,N',N'-ALKYLENEDIAMINE TRIALKANOIC ACID ESTERS | IRIX PHARMACEUTICALS | 2010-05-27 | — | — | US | disclosed |
| US-20100130770-A1 | N-ALKANOYL-N,N',N'-ALKYLENEDIAMINE TRIALKANOIC ACID ESTERS | IRIX PHARMACEUTICALS | 2010-05-27 | — | — | US | disclosed |
| WO-2010056854-A1 | N-ALKANOYL-N,N',N'-ALKYLENEDIAMINE TRIALKANOIC ACID ESTERS | IRIX PHARMACEUTICALS (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010056854-A1 | N-ALKANOYL-N,N',N'-ALKYLENEDIAMINE TRIALKANOIC ACID ESTERS | IRIX PHARMACEUTICALS (US) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130770-A1 | N-ALKANOYL-N,N',N'-ALKYLENEDIAMINE TRIALKANOIC ACID ESTERS | NAA15, NAAA, NRDC | NISCH 34/4885ADRA2A 604/4885ALDH1A1 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.