Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272999 | 0.89 | CA1 (0.57) | CES2CES1RAB9ACA1CA2 | |
| SCHEMBL30420427 | 0.87 | CA1 (0.55) | CES2CES1RAB9ACA1CA2 | |
| SCHEMBL29286745 | 0.87 | CES2 (0.50) | CES2CES1NPC1RAB9ACA1 | |
| SCHEMBL274249 | 0.82 | CES1 (0.48) | CES2CES1NPC1RAB9ACA1 | |
| SCHEMBL18687125 | 0.82 | CA1 (0.65) | CES2CES1RAB9ACA1CA2 | |
| SCHEMBL4127412 | 0.79 | TP53 (0.56) | PARP10L3MBTL1PKM | |
| Bromomethane SCHEMBL30082988 | 0.78 | CES1 (0.45) | CES2CES1NPC1RAB9APARP1 | |
| SCHEMBL50261 | 0.73 | CES2 (0.77) | CES2CES1NPC1RAB9ACA1 | |
| SCHEMBL2156563 | 0.73 | CES2 (1.00) | CES2CES1NPC1RAB9ACA1 | |
| Benzophenone SCHEMBL27935236 | 0.73 | CES2 (0.77) | CES2CES1NPC1RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113288817-B | Dental materials based on cyclizable polymeric crosslinkers | 义获嘉伟瓦登特公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117917236-A | Storage-stable self-adhesive composite cements with good transparency and good radiopacity | 义获嘉伟瓦登特公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-116350520-A | Self-adhesive dental composite cement with good transparency based on acid treated fillers | 义获嘉伟瓦登特公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-111529409-B | Dental material with improved mechanical properties | 义获嘉伟瓦登特公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-111529410-B | Dental material with improved setting properties | 义获嘉伟瓦登特公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-111529411-B | Dental material based on a redox system with low-odor cumene hydroperoxide derivatives | 义获嘉伟瓦登特公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114848503-A | Dental material based on polymerizable thiourea derivatives | 义获嘉伟瓦登特公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-111529411-A | Dental material based on a redox system with low-odor cumene hydroperoxide derivatives | 义获嘉伟瓦登特公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-111529410-A | Dental material with improved setting properties | 义获嘉伟瓦登特公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-111529409-A | Dental material with improved mechanical properties | 义获嘉伟瓦登特公司 | 2020-08-14 | — | — | CN | disclosed |