SCHEMBL28446641

SCHEMBL28446641

Cc1cc(C)cc([P](=O)C(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
TSHR P16473 3/20 0.35
TPMT P51580 1/20 0.33
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
C1S P09871 1/20 0.32
PRSS3 P35030 1/20 0.32
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HSP90AA1 P07900 1/20 0.30
CCR6 P51684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30568687 0.77 ACHE (0.40) ALDH1A1TSHRTDP1
SCHEMBL25219985 0.74 ALDH1A1 (0.35) ALDH1A1TSHRPRSS1PRSS2C1S
SCHEMBL14653011 0.72 ALDH1A1 (0.38) ALDH1A1TSHRTPMTNOS3NOS1
SCHEMBL11318825 0.72 ALDH1A1 (0.38) ALDH1A1TSHRTPMTNOS3NOS1
SCHEMBL1305677 0.71 ALDH1A1 (0.42) ALDH1A1TSHRTPMTPRSS1PRSS2
Bromide SCHEMBL29193903 0.70 ALDH1A1 (0.36) ALDH1A1TSHRNOS3NOS1NOS2
SCHEMBL28231579 0.70 ALDH1A1 (0.47) ALDH1A1TSHRTPMTPRSS1PRSS2
SCHEMBL12584883 0.67 ALDH1A1 (0.38) ALDH1A1TSHRTPMTNOS3NOS1
SCHEMBL1223821 0.67 ALDH1A1 (0.38) ALDH1A1TSHRTPMTNOS3NOS1
SCHEMBL19376983 0.65 ALDH1A1 (0.57) ALDH1A1TSHRTPMTPRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN disclosed