Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28866612 | 0.88 | AGTR1 (0.44) | AGTR1PCSK9L3MBTL1HTR6GAA | |
| SCHEMBL28259247 | 0.81 | L3MBTL1 (0.47) | AGTR1PCSK9L3MBTL1HTR6GAA | |
| SCHEMBL28436494 | 0.80 | HTR6 (0.42) | AGTR1PCSK9L3MBTL1HTR6GAA | |
| SCHEMBL28259260 | 0.79 | L3MBTL1 (0.46) | AGTR1PCSK9L3MBTL1HTR6GAA | |
| SCHEMBL28259608 | 0.78 | AGTR1 (0.44) | AGTR1PCSK9L3MBTL1HTR6GAA | |
| SCHEMBL28259252 | 0.75 | GAA (0.46) | AGTR1PCSK9L3MBTL1HTR6GAA | |
| SCHEMBL28451888 | 0.74 | AGTR1 (0.40) | AGTR1PCSK9L3MBTL1HTR6GAA | |
| SCHEMBL28449123 | 0.74 | AGTR1 (0.41) | AGTR1PCSK9L3MBTL1HTR6GAA | |
| SCHEMBL28259257 | 0.74 | AGTR1 (0.41) | AGTR1PCSK9L3MBTL1HTR6GAA | |
| SCHEMBL10375913 | 0.73 | HTR6 (0.50) | AGTR1PCSK9L3MBTL1HTR6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081807-B | Method for preparing tri-substituted 4-aminocarbazole and di-substituted 1-aminodibenzo [ b, d ] thiophene compounds | 台州学院 | 2020-08-04 | — | — | CN | disclosed |
| CN-109081807-A | A kind of three substitution 4- aminocarbazole classes and two that prepare replace the method for 1- aminodiphenyls simultaneously [b, d] thiophenes | 台州学院 | 2018-12-25 | — | — | CN | disclosed |