Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521320 | 0.78 | KDM4C (0.55) | PARP1KMT2AMEN1DRD1KDM4C | |
| SCHEMBL9150411 | 0.77 | ACHE (0.52) | KMT2AMEN1ACHE | |
| SCHEMBL22914896 | 0.76 | KDM4C (0.50) | PARP1KMT2AMEN1DRD1KDM4C | |
| SCHEMBL27536254 | 0.76 | PARP1 (0.49) | PARP1KMT2AMEN1DRD1KDM4C | |
| SCHEMBL17361560 | 0.75 | KDM4C (0.49) | PARP1KMT2AMEN1DRD1KDM4C | |
| SCHEMBL16254293 | 0.74 | TAS1R3 (0.54) | KMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL10838684 | 0.72 | KDM1A (0.35) | PARP1KMT2AMEN1KDM4C | |
| SCHEMBL28458143 | 0.70 | KDM4C (0.43) | KMT2AMEN1KDM4C | |
| SCHEMBL19943971 | 0.70 | ABCB1 (0.45) | PARP1KMT2AMEN1 | |
| SCHEMBL28447485 | 0.69 | DRD5 (0.45) | KMT2AMEN1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909083-B | Inhibitors of histone demethylase | 赛尔基因昆蒂赛尔研究公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-111909083-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-106660982-B | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2020-09-08 | — | — | CN | disclosed |