Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD5 | P21918 | 3/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28458143 | 0.84 | KDM4C (0.43) | KDM4CCA1CA2NR1I2KMT2A | |
| SCHEMBL17361727 | 0.75 | KDM4C (0.50) | DRD5KDM4C | |
| SCHEMBL30558482 | 0.75 | KDM4C (0.50) | DRD5KDM4C | |
| SCHEMBL5889358 | 0.74 | HTT (0.49) | KMT2AMEN1 | |
| SCHEMBL8074452 | 0.74 | HTT (0.49) | KMT2AMEN1 | |
| SCHEMBL16254293 | 0.73 | TAS1R3 (0.54) | KMT2AMEN1 | |
| SCHEMBL8011020 | 0.73 | DRD5 (0.46) | DRD5KDM4CCA1CA2KMT2A | |
| SCHEMBL7105876 | 0.73 | DRD5 (0.46) | DRD5KDM4CCA1CA2KMT2A | |
| Hydrochloric Acid SCHEMBL8074492 | 0.72 | DRD5 (0.48) | DRD5KDM4CKMT2AMEN1 | |
| SCHEMBL23674495 | 0.71 | CYP3A4 (0.44) | DRD5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909083-B | Inhibitors of histone demethylase | 赛尔基因昆蒂赛尔研究公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-111909083-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-106660982-B | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2020-09-08 | — | — | CN | disclosed |