Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 8/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17361727 | 1.00 | KDM4C (0.50) | KDM4CHTR6ABCB1HTR2AHTR2C | |
| SCHEMBL17361970 | 0.84 | KDM4C (0.49) | KDM4CHTR6ABCB1ADRA2AADRA2B | |
| SCHEMBL17221872 | 0.79 | ADRA2A (0.57) | HTR2AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL4685354 | 0.78 | NQO2 (0.50) | KDM4CABCB1HTR2AHTR2CHTR2B | |
| SCHEMBL17361429 | 0.78 | KDM4C (0.58) | KDM4CHTR6 | |
| SCHEMBL30558394 | 0.78 | KDM4C (0.58) | KDM4CHTR6 | |
| SCHEMBL28447485 | 0.75 | DRD5 (0.45) | KDM4CDRD5 | |
| SCHEMBL8011020 | 0.75 | DRD5 (0.46) | KDM4CADRA1ADRD5 | |
| SCHEMBL7105876 | 0.75 | DRD5 (0.46) | KDM4CADRA1ADRD5 | |
| Hydrochloric Acid SCHEMBL8074492 | 0.74 | DRD5 (0.48) | KDM4CHTR2ADRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909083-B | Inhibitors of histone demethylase | 赛尔基因昆蒂赛尔研究公司 | 2023-08-15 | — | — | CN | disclosed |