Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 7/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18901291 | 0.75 | NOTUM (0.59) | NPC1RAB9ALMNAALDH1A1NFKB1 | |
| SCHEMBL12321663 | 0.75 | CDK2 (0.58) | CDC7CCNE1CDK2DBF4 | |
| SCHEMBL22462553 | 0.73 | PCSK9 (0.40) | MPOSLC6A4RAB9ANOTUMGPR84 | |
| SCHEMBL3821037 | 0.66 | RAB9A (0.67) | NPC1RAB9AALDH1A1CASP3SMN1; SMN2 | |
| SCHEMBL1968447 | 0.64 | MPO (1.00) | MPOSLC6A4NFKB1SMN1; SMN2GPR84 | |
| SCHEMBL3822281 | 0.64 | NOTUM (0.65) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL15595978 | 0.64 | NOTUM (0.51) | NPC1RAB9ALMNAALDH1A1NFKB1 | |
| SCHEMBL31049406 | 0.64 | GPR84 (0.64) | MPOSLC6A4RAB9AGPR84 | |
| Hydrochloric Acid SCHEMBL23091149 | 0.63 | MPO (0.97) | MPOSLC6A4NFKB1SMN1; SMN2GPR84 | |
| SCHEMBL3826961 | 0.63 | HPGD (0.61) | NPC1RAB9AALDH1A1CASP3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587249-A | Indole compounds and uses thereof | 阿里根公司 | 2020-08-25 | — | — | CN | disclosed |