Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086268 | 0.65 | SIGMAR1 (0.36) | PTGS2PTGS1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28880916 | 0.63 | SIGMAR1 (0.35) | PTGS2PTGS1 | |
| 1,4-Dichlorobenzene SCHEMBL3910732 | 0.62 | MAOB (0.36) | MEN1KMT2ARAB9ANPC1TP53 | |
| SCHEMBL3947663 | 0.62 | HPGD (0.59) | RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL28874436 | 0.61 | NPC1 (0.37) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4339852 | 0.60 | PTGS1 (0.43) | PTGS2PTGS1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5981523 | 0.60 | SIGMAR1 (0.38) | PTGS2SLC6A3 | |
| SCHEMBL13896954 | 0.60 | SIGMAR1 (0.38) | PTGS2SLC6A3MEN1KMT2AL3MBTL1 | |
| SCHEMBL25487624 | 0.59 | PTGS2 (0.42) | PTGS2PTGS1SLC6A3SLC6A2 | |
| SCHEMBL31539908 | 0.59 | KDM1A (0.38) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531705-B | Bicyclic ketone sulfonamide compounds | 美国安进公司 | 2020-09-18 | — | — | CN | disclosed |