SCHEMBL28880916

SCHEMBL28880916

FC1(F)CC(c2ccc(Cl)cc2)=CC=C1Cl

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.35
HTR2C P28335 1/20 0.34
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
KDM1A O60341 1/20 0.33
CYP1A2 P05177 1/20 0.32
LMNA P02545 1/20 0.31
CYP2A6 P11509 1/20 0.31
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7086268 0.78 SIGMAR1 (0.36) SIGMAR1HTR2CCYP1A2LMNACYP2A6
1,4-Dichlorobenzene SCHEMBL3910732 0.65 MAOB (0.36) SIGMAR1HTR2CMAOAMAOB
SCHEMBL28560407 0.62 SIGMAR1 (0.52) SIGMAR1HTR2CCYP1A2LMNACYP2A6
SCHEMBL28603878 0.62 LMNA (0.47) MAOAMAOBKDM1ACYP1A2LMNA
SCHEMBL2697348 0.61 SIGMAR1 (0.43) SIGMAR1HTR2CMAOAMAOBKDM1A
SCHEMBL31312584 0.61 SIGMAR1 (0.35) SIGMAR1HTR2CMAOAMAOBKDM1A
SCHEMBL13896954 0.61 SIGMAR1 (0.38) SIGMAR1HTR2CCYP1A2LMNACYP2A6
SCHEMBL5981523 0.61 SIGMAR1 (0.38) SIGMAR1HTR2CCYP1A2LMNACYP2A6
SCHEMBL7799451 0.60 SIGMAR1 (0.56) SIGMAR1HTR2CCYP1A2LMNACYP2A6
SCHEMBL11165087 0.59 CYP1A2 (0.73) MAOBCYP1A2LMNACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322070-B Preparation method of p-alkylphenyl o-fluorobenzene 烟台盛华液晶材料有限公司 2024-04-23 CN disclosed
CN-115322070-A Preparation method of p-alkyl phenyl o-fluorobenzene 烟台盛华液晶材料有限公司 2022-11-11 CN disclosed