SCHEMBL28447780

SCHEMBL28447780

Cc1cccc(C(CCCS(=O)(=O)O)c2cn(C3CCCCC3)c3ccc(-c4ccnn4C)cc23)c1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.34
BRD3 Q15059 1/20 0.34
CTSA P10619 1/20 0.34
NAAA Q02083 1/20 0.33
SCN5A Q14524 1/20 0.33
SCN9A Q15858 1/20 0.33
MAPK1 P28482 1/20 0.32
HDAC8 Q9BY41 4/20 0.32
DRD2 P14416 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
KMT2A Q03164 1/20 0.32
ATR Q13535 2/20 0.31
SCD5 Q86SK9 1/20 0.31
IRAK4 Q9NWZ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23722059 0.89 NAAA (0.36) BRD4BRD3CTSANAAAMAPK1
SCHEMBL22439409 0.87 BRD4 (0.36) BRD4BRD3CTSANAAAMAPK1
SCHEMBL23745356 0.84 CTSA (0.38) BRD4BRD3CTSANAAAMAPK1
SCHEMBL23722062 0.83 CTSA (0.34) BRD4BRD3CTSANAAASCN5A
SCHEMBL23745353 0.81 MPO (0.33) BRD4BRD3CTSANAAAMAPK1
Hydrochloric Acid SCHEMBL23722089 0.81 MPO (0.32) BRD4BRD3NAAAMAPK1DRD2
Hydrochloric Acid SCHEMBL23722103 0.81 MPO (0.32) BRD4BRD3NAAAMAPK1DRD2
SCHEMBL23745602 0.81 NAAA (0.32) BRD4BRD3NAAAMAPK1DRD2
SCHEMBL23722049 0.80 MAPK1 (0.33) BRD4BRD3CTSANAAAMAPK1
SCHEMBL23745659 0.79 KDM4D (0.35) BRD4BRD3MAPK1DRD2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111566085-A Anti-infective heterocyclic compounds and uses thereof 百欧伊米克思有限公司 2020-08-21 CN disclosed