Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23722059 | 0.87 | NAAA (0.36) | CTSAMAPK1HDAC8ALDH1A1NAAA | |
| SCHEMBL22439442 | 0.84 | ELANE (0.39) | ALDH1A1MEN1KMT2AELANE | |
| SCHEMBL23745376 | 0.84 | KDM4E (0.43) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL28447780 | 0.84 | BRD4 (0.34) | CTSAMAPK1HDAC8ALDH1A1NAAA | |
| SCHEMBL22439409 | 0.84 | BRD4 (0.36) | CTSAMAPK1HDAC8ALDH1A1NAAA | |
| SCHEMBL23722062 | 0.83 | CTSA (0.34) | CTSAMAPK1HDAC8NAAABRD4 | |
| SCHEMBL23722049 | 0.82 | MAPK1 (0.33) | CTSAMAPK1HDAC8NAAABRD4 | |
| SCHEMBL23745659 | 0.80 | KDM4D (0.35) | MAPK1BRD4BRD3DRD2MEN1 | |
| SCHEMBL23745353 | 0.79 | MPO (0.33) | CTSAMAPK1NAAABRD4BRD3 | |
| Hydrochloric Acid SCHEMBL23722103 | 0.79 | MPO (0.32) | MAPK1NAAABRD4BRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246115-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246115-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | FDPS, FPR1, F12 | CTSA 664/4885MAPK1 3177/4885HDAC8 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.