Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447536 | 0.85 | L3MBTL1 (0.51) | KMT2AMEN1RAB9AALDH1A1MAPT | |
| SCHEMBL28456754 | 0.75 | KMT2A (0.40) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL1931922 | 0.73 | ALDH1A1 (0.61) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL29770828 | 0.73 | ALDH1A1 (0.61) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL168169 | 0.72 | KDM4E (0.41) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL13870606 | 0.72 | KMT2A (0.48) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL12554590 | 0.72 | KDM4E (0.51) | KMT2ANPC1RAB9AALDH1A1GAA | |
| SCHEMBL10908139 | 0.72 | KMT2A (0.48) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL28347039 | 0.72 | KMT2A (0.48) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL1647955 | 0.70 | METAP2 (0.46) | KMT2AMEN1ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606928-A | Azacyclodiketone compound and preparation method thereof | 维清生物科技(上海)有限公司 | 2020-09-01 | — | — | CN | disclosed |