Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28379144 | 0.82 | POLB (0.52) | GPR119HRH3 | |
| SCHEMBL16684777 | 0.82 | HRH3 (0.43) | AOC3HRH3 | |
| SCHEMBL4392645 | 0.81 | GPR119 (0.53) | GPR119AOC3CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL30663949 | 0.81 | GPR119 (0.53) | GPR119AOC3CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL21828535 | 0.81 | GPR119 (0.51) | GPR119CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28719495 | 0.80 | HRH3 (0.51) | GPR119AOC3CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL27600357 | 0.78 | CHRNB2 (0.51) | GPR119CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL19302597 | 0.78 | GPR119 (0.52) | GPR119CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL31329886 | 0.78 | GPR119 (0.52) | GPR119CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL20483697 | 0.78 | HRH3 (0.50) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107629059-B | Compounds useful as inhibitors of ATR kinase | 沃泰克斯药物股份有限公司 | 2020-07-28 | — | — | CN | disclosed |