Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28448328 | 0.87 | ALDH1A1 (0.52) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8315096 | 0.83 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8973738 | 0.75 | CYP19A1 (0.57) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL708511 | 0.75 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8973852 | 0.74 | CYP19A1 (0.56) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1220299 | 0.73 | ALDH1A1 (0.55) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL29379815 | 0.73 | ALDH1A1 (0.55) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL20591951 | 0.72 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11602621 | 0.71 | KMT2A (0.64) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL27692446 | 0.70 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484414-A | 2, 4-dinitrophenol derivatives and uses thereof | 南京诺瑞特医药科技有限公司 | 2020-08-04 | — | — | CN | disclosed |