Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28448328 | 0.96 | ALDH1A1 (0.52) | MAPTALDH1A1TDP1TTRPOLB | |
| SCHEMBL20591951 | 0.85 | MAPT (0.54) | MAPTALDH1A1TDP1TTRPOLB | |
| SCHEMBL28448329 | 0.83 | MAPT (0.48) | MAPTALDH1A1TDP1TTRPOLB | |
| SCHEMBL27491468 | 0.82 | TDP1 (0.46) | MAPTALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL7134426 | 0.81 | SMN1; SMN2 (0.49) | MAPTALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL27692446 | 0.81 | MAPT (0.42) | MAPTALDH1A1TDP1TTRPOLB | |
| SCHEMBL29246356 | 0.79 | SMN1; SMN2 (0.41) | MAPTALDH1A1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL11829181 | 0.79 | KMT2A (0.42) | MAPTALDH1A1TDP1L3MBTL1KMT2A | |
| SCHEMBL427368 | 0.79 | ALDH1A1 (0.55) | MAPTALDH1A1TDP1TTRPOLB | |
| SCHEMBL29379815 | 0.79 | ALDH1A1 (0.55) | MAPTALDH1A1TDP1TTRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923536-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004517-A1 | ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION | PHARMACIA & UPJOHN AB (SE) | 1998-02-05 | — | — | WO | disclosed |