Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717058 | 0.84 | TSHR (0.58) | ALDH1A1LMNANPC1TSHRRAB9A | |
| SCHEMBL18412868 | 0.84 | LMNA (0.44) | ALDH1A1LMNANPC1TSHRRAB9A | |
| SCHEMBL2806923 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNANPC1TSHRRAB9A | |
| SCHEMBL28036515 | 0.83 | MAPK14 (0.45) | ALDH1A1LMNANPC1TSHR | |
| SCHEMBL173434 | 0.78 | NPC1 (0.68) | ALDH1A1LMNANPC1TSHRRAB9A | |
| SCHEMBL27714945 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNANPC1TSHRSMN1; SMN2 | |
| SCHEMBL27714949 | 0.76 | PROKR1 (0.39) | ALDH1A1LMNANPC1TSHRRAB9A | |
| SCHEMBL24453565 | 0.73 | ALDH1A1 (0.44) | ALDH1A1LMNANPC1TSHRRAB9A | |
| SCHEMBL2862025 | 0.70 | TSHR (0.55) | ALDH1A1LMNANPC1TSHRRAB9A | |
| SCHEMBL1802878 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066282-B | Pyrazolopyrimidinone compound and preparation method and application thereof | 南开大学 | 2020-07-10 | — | — | CN | disclosed |