Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28450709 | 0.89 | POLB (0.41) | POLBMAPTSMN1; SMN2VCAM1NSD2 | |
| SCHEMBL28456405 | 0.87 | TXNRD1 (0.42) | MAPTSMN1; SMN2ALDH1A1TXNRD1HTT | |
| SCHEMBL28475797 | 0.82 | ALDH1A1 (0.38) | POLBMAPTSMN1; SMN2ALDH1A1TXNRD1 | |
| SCHEMBL28448537 | 0.79 | TXNRD1 (0.43) | MAPTSMN1; SMN2ALDH1A1TXNRD1GSR | |
| SCHEMBL27913490 | 0.76 | TXNRD1 (0.39) | MAPTALDH1A1TXNRD1GSRAGTR1 | |
| SCHEMBL28448531 | 0.76 | MAPT (0.41) | FGFR4POLBMAPTVCAM1NSD2 | |
| SCHEMBL28458192 | 0.75 | MAPT (0.43) | POLBMAPTSMN1; SMN2VCAM1NSD2 | |
| SCHEMBL28460738 | 0.75 | MAPT (0.43) | POLBMAPTVCAM1NSD2NCOA1 | |
| SCHEMBL28458433 | 0.75 | TRPA1 (0.37) | MAPTALDH1A1GAA | |
| SCHEMBL28451066 | 0.74 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1TXNRD1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662283-A | Imidazopyridine compound and intermediate, preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-113480541-B | Process for producing imidazopyridine compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-111662283-B | Imidazopyridine compound and intermediate, preparation method and application thereof | 湖南化工研究院有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-113480541-A | Process for producing imidazopyridine compound and intermediate thereof | 湖南化工研究院有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-111662283-A | Imidazopyridine compound and intermediate, preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |