Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 9/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 9/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27767830 | 0.84 | FNTA (0.60) | MAPTFNTAFNTBKDM4EALDH1A1 | |
| SCHEMBL29412239 | 0.81 | MAPT (0.68) | MAPTTHRBBAZ2BBAZ2ATP53 | |
| SCHEMBL17339106 | 0.78 | FNTA (0.60) | MAPTTHRBBAZ2BBAZ2ATP53 | |
| SCHEMBL17339164 | 0.77 | MAPT (0.46) | MAPTTHRBBAZ2BBAZ2ATP53 | |
| SCHEMBL18549567 | 0.74 | TP53 (0.44) | MAPTTHRBBAZ2BBAZ2ATP53 | |
| SCHEMBL9531095 | 0.71 | FNTA (0.69) | MAPTTHRBBAZ2BBAZ2ATP53 | |
| SCHEMBL17339148 | 0.71 | ALDH1A1 (0.61) | MAPTTHRBBAZ2BBAZ2ATP53 | |
| SCHEMBL18549629 | 0.71 | MAPT (0.50) | MAPTTHRBBAZ2BBAZ2ATP53 | |
| SCHEMBL18549638 | 0.70 | KDM4E (0.53) | MAPTTHRBTP53FNTAFNTB | |
| SCHEMBL12394725 | 0.69 | FNTA (0.54) | MAPTTHRBBAZ2BBAZ2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892579-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-111875585-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111892579-A | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111875585-A | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-106660993-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2020-09-11 | — | — | CN | disclosed |