Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.69 |
| ▸ | FNTB | P49356 | 4/20 | 0.69 |
| ▸ | BAZ2B | Q9UIF8 | 10/20 | 0.60 |
| ▸ | BAZ2A | Q9UIF9 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | BRD4 | O60885 | 2/20 | 0.56 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.56 |
| ▸ | BRD2 | P25440 | 1/20 | 0.56 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412239 | 0.90 | MAPT (0.68) | FNTAFNTBBAZ2BBAZ2AMAPT | |
| SCHEMBL17339106 | 0.87 | FNTA (0.60) | FNTAFNTBBAZ2BBAZ2AMAPT | |
| SCHEMBL24304134 | 0.83 | TP53 (0.63) | FNTAFNTBBAZ2BBAZ2AMAPT | |
| SCHEMBL26302103 | 0.81 | BAZ2B (0.75) | FNTAFNTBBAZ2BBAZ2AMAPT | |
| SCHEMBL7439300 | 0.79 | BAZ2B (0.64) | FNTAFNTBBAZ2BBAZ2AMAPT | |
| SCHEMBL9531120 | 0.79 | FNTA (0.59) | FNTAFNTBBAZ2BBAZ2AMAPT | |
| SCHEMBL9535179 | 0.79 | KDM4E (0.69) | FNTAFNTBBAZ2BBAZ2AMAPT | |
| SCHEMBL25401668 | 0.78 | BAZ2B (0.62) | FNTAFNTBBAZ2BBAZ2AMAPT | |
| SCHEMBL10797200 | 0.76 | FNTA (0.59) | FNTAFNTB | |
| SCHEMBL9531986 | 0.76 | FNTA (0.60) | FNTAFNTBBAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289170-B1 | AZABICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1993-06-23 | — | — | EP | disclosed |
| US-4882327-A | NERVOUS SYSTEM DISORDERS | BEECHAM GROUP P.L.C. (GB) | 1989-11-21 | — | — | US | disclosed |
| EP-0289170-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-11-02 | — | — | EP | disclosed |