SCHEMBL28448902

SCHEMBL28448902

CCCOC(=O)C(C)[SiH2]OC(C)C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.34
LMNA P02545 3/20 0.33
ALDH1A1 P00352 3/20 0.33
ESR1 P03372 1/20 0.32
CHRM1 P11229 1/20 0.32
TSHR P16473 1/20 0.32
SLC6A2 P23975 1/20 0.32
KDR P35968 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NAAA Q02083 1/20 0.31
DGKA P23743 1/20 0.31
PPM1B O75688 1/20 0.31
PTPN1 P18031 1/20 0.31
PPP1CC P36873 1/20 0.31
MAPT P10636 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22614864 0.89 NAAA (0.46) HCAR2LMNAALDH1A1TSHRNAAA
SCHEMBL21179455 0.89 ALDH1A1 (0.45) HCAR2LMNAALDH1A1TSHRTDP1
SCHEMBL22614818 0.87 NAAA (0.48) HCAR2LMNAALDH1A1TSHRNAAA
SCHEMBL21177553 0.87 NAAA (0.48) HCAR2LMNAALDH1A1TSHRNAAA
SCHEMBL21177537 0.87 NAAA (0.48) HCAR2LMNAALDH1A1TSHRNAAA
SCHEMBL21177520 0.87 NAAA (0.48) HCAR2LMNAALDH1A1TSHRNAAA
SCHEMBL21177501 0.83 ALDH1A1 (0.39) LMNAALDH1A1HSD17B10
SCHEMBL22614787 0.77 HCAR2 (0.32) HCAR2LMNAALDH1A1TSHRTDP1
SCHEMBL21180339 0.74 SMN1; SMN2 (0.39) ALDH1A1
SCHEMBL21177752 0.74 TSHR (0.40) HCAR2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111601866-B Silicone adhesive composition, cured product, adhesive film, and adhesive tape 信越化学工业株式会社 2022-09-06 CN disclosed
CN-111601866-A Silicone adhesive composition, adhesive film, and adhesive tape 信越化学工业株式会社 2020-08-28 CN disclosed