SCHEMBL21180339

SCHEMBL21180339

COC(=O)C(C)[SiH2]OC(C)C

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.39
CA14 Q9ULX7 2/20 0.37
CA12 O43570 1/20 0.34
ZDHHC7 Q9NXF8 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21177752 0.81 TSHR (0.40)
SCHEMBL21177501 0.77 ALDH1A1 (0.39) ALDH1A1
SCHEMBL3377496 0.73 TSHR (0.31)
SCHEMBL21179463 0.73 SMN1; SMN2 (0.37) SMN1; SMN2CA14CA12
SCHEMBL22614864 0.71 NAAA (0.46) ALDH1A1
SCHEMBL21179455 0.71 ALDH1A1 (0.45) ALDH1A1
SCHEMBL10798382 0.71 SMN1; SMN2 (0.35) SMN1; SMN2CA14CA12
SCHEMBL21177520 0.70 NAAA (0.48) ALDH1A1
SCHEMBL21177553 0.70 NAAA (0.48) ALDH1A1
SCHEMBL10363028 0.67 SMN1; SMN2 (0.39) SMN1; SMN2CA14CA12ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702574-B2 Adhesive silicone composition and an adhesive film or tape SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
US-20200347281-A1 ADHESIVE SILICONE COMPOSITION AND AN ADHESIVE FILM OR TAPE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-11-05 US disclosed
WO-2019142779-A1 SILICONE ADHESIVE COMPOSITION, ADHESIVE FILM, AND ADHESIVE TAPE 信越化学工業株式会社 2019-07-25 WO disclosed