Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 10/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453343 | 0.77 | RPS6KA3 (0.35) | GSK3B | |
| SCHEMBL28452749 | 0.65 | GSK3B (0.38) | GSK3B | |
| SCHEMBL18278576 | 0.62 | HTR6 (0.33) | HTR6RBP4 | |
| SCHEMBL15771306 | 0.62 | ATR (0.48) | ATRRBP4 | |
| SCHEMBL15779047 | 0.61 | SIGMAR1 (0.32) | ATR | |
| SCHEMBL15770453 | 0.61 | ATR (0.47) | ATR | |
| SCHEMBL31301252 | 0.61 | GSK3B (0.59) | GSK3B | |
| SCHEMBL29131003 | 0.59 | ATR (0.39) | ATRHTR6 | |
| SCHEMBL30602455 | 0.59 | ATR (0.39) | ATRHTR6 | |
| SCHEMBL15770521 | 0.59 | MAPT (0.37) | ATRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107629059-B | Compounds useful as inhibitors of ATR kinase | 沃泰克斯药物股份有限公司 | 2020-07-28 | — | — | CN | disclosed |