SCHEMBL28449441

SCHEMBL28449441

CC(C)(C)C(=O)Nc1ccc(C#C[Si](C)(C)C)cn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.45
NPC1 O15118 2/20 0.45
PAX8 Q06710 1/20 0.45
KLF5 Q13887 1/20 0.45
KDR P35968 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPT P10636 1/20 0.38
GRIN2B Q13224 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14840429 0.89 MAP4K1 (0.39) RAB9ANPC1PAX8KLF5KDR
SCHEMBL2806910 0.85 RAB9A (0.44) RAB9ANPC1L3MBTL1TP53SMN1; SMN2
SCHEMBL14840464 0.84 FFAR1 (0.49) RAB9ANPC1PAX8KLF5KDR
SCHEMBL12403192 0.83 GABRA5 (0.45) GRIN2BGABRA1GABRG2GABRB3GABRA5
SCHEMBL856063 0.82 MEN1 (0.53) RAB9ANPC1PAX8KLF5KDR
SCHEMBL25209850 0.79 LMNA (0.45) RAB9ANPC1PAX8KLF5L3MBTL1
SCHEMBL14840556 0.78 GRM5 (0.57)
SCHEMBL14784662 0.76 HTT (0.44) RAB9ANPC1L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL503281 0.76 MTOR (0.41) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL1721767 0.74 RAB9A (0.68) RAB9ANPC1PAX8KLF5KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111416154-B Silicon-based pyridine additive for high-voltage lithium ion battery electrolyte, electrolyte and battery 松山湖材料实验室 2021-08-06 CN claimed
CN-111416154-A Silicon-based pyridine additive for high-voltage lithium ion battery electrolyte, electrolyte and battery 松山湖材料实验室 2020-07-14 CN claimed
CN-111416154-B Silicon-based pyridine additive for high-voltage lithium ion battery electrolyte, electrolyte and battery 松山湖材料实验室 2021-08-06 CN disclosed
CN-111416154-A Silicon-based pyridine additive for high-voltage lithium ion battery electrolyte, electrolyte and battery 松山湖材料实验室 2020-07-14 CN disclosed