Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28446792 | 0.98 | FAAH (0.47) | FAAHTRPV1DNM1KDM1APPARA | |
| SCHEMBL5487697 | 0.90 | DNM1 (0.47) | FAAHTRPV1DNM1KDM1APPARA | |
| Hydrochloric Acid SCHEMBL6039660 | 0.88 | DNM1 (0.48) | FAAHTRPV1DNM1KDM1APPARA | |
| SCHEMBL14671511 | 0.86 | FAAH (0.48) | FAAHTRPV1DNM1PPARAEPHX2 | |
| SCHEMBL29077674 | 0.81 | KDM1A (0.61) | FAAHTRPV1KDM1APPARAEPHX2 | |
| Bromide SCHEMBL10495193 | 0.79 | DNM1 (0.58) | FAAHTRPV1DNM1PPARAEPHX2 | |
| Bromide SCHEMBL10495249 | 0.79 | DNM1 (0.58) | FAAHTRPV1DNM1PPARAEPHX2 | |
| Bromide SCHEMBL10495210 | 0.79 | DNM1 (0.58) | FAAHTRPV1DNM1PPARAEPHX2 | |
| Bromide SCHEMBL28018908 | 0.79 | DNM1 (0.73) | FAAHTRPV1DNM1PPARAEPHX2 | |
| Bromide SCHEMBL10495219 | 0.79 | DNM1 (0.58) | FAAHTRPV1DNM1PPARAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635749-A | Slick water system with resistance reduction and sand carrying functions and preparation method thereof | 四川光亚聚合物化工有限公司 | 2020-09-08 | — | — | CN | claimed |
| CN-111635749-A | Slick water system with resistance reduction and sand carrying functions and preparation method thereof | 四川光亚聚合物化工有限公司 | 2020-09-08 | — | — | CN | disclosed |
| CN-107245331-B | Oil displacement system and method for medium-permeability oil reservoir | 四川光亚聚合物化工有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-106867497-B | Oil displacement system and method for low-permeability oil reservoir | 四川光亚聚合物化工有限公司 | 2020-05-22 | — | — | CN | disclosed |