Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452508 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACA12CA2 | |
| SCHEMBL28461694 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ACA12CA2 | |
| SCHEMBL28463579 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACA12CA2 | |
| SCHEMBL28529020 | 0.74 | MMP2 (0.54) | ALDH1A1MEN1KMT2ACA12CA2 | |
| SCHEMBL28530379 | 0.72 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACA12CA2 | |
| SCHEMBL20512270 | 0.72 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ACA12CA2 | |
| SCHEMBL5567042 | 0.70 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2ACA12CA2 | |
| SCHEMBL6020322 | 0.70 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ACA12CA2 | |
| SCHEMBL20512257 | 0.70 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ACA12CA2 | |
| SCHEMBL20512230 | 0.69 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299423-B | Synthesis method of dihydropyrrolo-2-aminoquinoline compound | 华南理工大学 | 2020-09-22 | — | — | CN | disclosed |