Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20512230 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL3377119 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL5567042 | 0.79 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL20512257 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL6020322 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL28529020 | 0.78 | MMP2 (0.54) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL20512265 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL8213969 | 0.77 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL4703731 | 0.77 | CA12 (0.71) | ALDH1A1MEN1KMT2ACA2CA12 | |
| SCHEMBL20512240 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180354963-A1 | NOVEL LACTONES | PURDUE RESEARCH FOUNDATION (US) | 2018-12-13 | — | — | US | disclosed |
| US-10138252-B1 | Lactones | PURDUE RESEARCH FOUNDATION (US) | 2018-11-27 | — | — | US | disclosed |
| US-20180305371-A1 | NOVEL LACTONES | PURDUE RESEARCH FOUNDATION (US) | 2018-10-25 | — | — | US | disclosed |
| US-10087190-B1 | Lactones | PURDUE RESEARCH FOUNDATION (US) | 2018-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180354963-A1 | NOVEL LACTONES | DHPS, FDPS, LSS | ALDH1A1 2443/4885MEN1 849/4885KMT2A 3125/4885 |
| US-20180305371-A1 | NOVEL LACTONES | DHPS, FDPS, LSS | ALDH1A1 2443/4885MEN1 849/4885KMT2A 3125/4885 |
| US-10138252-B1 | Lactones | DHPS, FDPS, LSS | ALDH1A1 2208/4885MEN1 624/4885KMT2A 3286/4885 |
| US-10087190-B1 | Lactones | DHPS, FDPS, LSS | ALDH1A1 2208/4885MEN1 624/4885KMT2A 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.