Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.58 |
| ▸ | ITK | Q08881 | 5/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | TEC | P42680 | 1/20 | 0.47 |
| ▸ | TXK | P42681 | 1/20 | 0.47 |
| ▸ | BMX | P51813 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | CD69 | Q07108 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455574 | 0.95 | EGFR (0.58) | EGFRITKTGM2JAK2LYN | |
| SCHEMBL28463718 | 0.95 | EGFR (0.63) | EGFRITKTGM2JAK2LYN | |
| SCHEMBL14260335 | 0.90 | MAPT (0.59) | EGFRITKTGM2FAAHJAK3 | |
| SCHEMBL5043916 | 0.86 | TGM2 (0.63) | EGFRITKTGM2 | |
| SCHEMBL28456327 | 0.86 | EGFR (0.69) | EGFRITKTGM2JAK2LYN | |
| SCHEMBL28458937 | 0.86 | EGFR (0.55) | EGFRITKTGM2JAK2LYN | |
| SCHEMBL4033138 | 0.83 | SLC2A1 (0.65) | MCHR1 | |
| SCHEMBL27616728 | 0.79 | TDP1 (0.51) | EGFRTGM2 | |
| SCHEMBL28310060 | 0.79 | TGM2 (0.67) | EGFRITKTGM2JAK2LYN | |
| SCHEMBL1381244 | 0.77 | TGM2 (0.59) | EGFRITKTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041331-B | Styrylxanthine derivative and use thereof | 广东东阳光药业有限公司 | 2020-08-07 | — | — | CN | disclosed |