Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909694 | 0.82 | RAD51 (0.42) | SMN1; SMN2NPC1RAB9ALMNANFKB1 | |
| SCHEMBL28173006 | 0.79 | TP53 (0.42) | SMN1; SMN2NPC1RAB9ALMNANFKB1 | |
| SCHEMBL11352100 | 0.77 | HTR7 (0.35) | SMN1; SMN2KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL27596036 | 0.77 | KMT2A (0.39) | SMN1; SMN2NPC1RAB9ALMNANFKB1 | |
| SCHEMBL11047835 | 0.77 | METAP2 (0.38) | SMN1; SMN2NPC1RAB9ALMNANFKB1 | |
| SCHEMBL4270861 | 0.71 | P2RX7 (0.32) | — | |
| SCHEMBL3241311 | 0.71 | NPC1 (0.45) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL8250696 | 0.70 | METAP2 (0.44) | SMN1; SMN2NPC1RAB9ALMNAKDM4E | |
| SCHEMBL3234188 | 0.70 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL29668083 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912052-B | Preparation method of cyazofamid | 江苏扬农化工集团有限公司 | 2020-08-14 | — | — | CN | disclosed |