Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.48 |
| ▸ | HTR2B | P41595 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973306 | 0.83 | HTR2C (0.38) | HTR2CHTR2BDRD2HTR2AHTR1A | |
| SCHEMBL5845061 | 0.81 | ESR1 (0.56) | DRD2DRD3OPRK1ESR1ESR2 | |
| SCHEMBL1737108 | 0.78 | DRD2 (0.55) | HTR2CHTR2BDRD2HTR2AHTR1A | |
| SCHEMBL6861402 | 0.77 | ALDH1A1 (0.39) | HTR2CHTR2BDRD2HTR2AHTR1A | |
| SCHEMBL29644533 | 0.76 | CA2 (0.41) | HTR1AADRA2ACHRM1ADRA2BADRA2C | |
| SCHEMBL4289906 | 0.76 | CA2 (0.41) | HTR1AADRA2ACHRM1ADRA2BADRA2C | |
| SCHEMBL5695479 | 0.76 | CA2 (0.41) | HTR1AADRA2ACHRM1ADRA2BADRA2C | |
| SCHEMBL6861044 | 0.76 | TDP1 (0.51) | ESR1ESR2ALDH1A1MAPK1SRD5A1 | |
| SCHEMBL14069697 | 0.76 | DRD2 (0.56) | HTR2CHTR2BDRD2HTR2AHTR1A | |
| SCHEMBL27847510 | 0.75 | DRD2 (0.62) | HTR2CHTR2BDRD2HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108383822-B | Preparation method of 2-chloro-1- (6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-yl) ethanone | 浙江车头制药股份有限公司 | 2020-09-18 | — | — | CN | claimed |
| CN-108383822-B | Preparation method of 2-chloro-1- (6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-yl) ethanone | 浙江车头制药股份有限公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-108383822-B | Preparation method of 2-chloro-1- (6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-yl) ethanone | 浙江车头制药股份有限公司 | 2020-09-18 | — | — | CN | disclosed |