Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | GLA | P06280 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | IDO1 | P14902 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | TDO2 | P48775 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28147490 | 0.86 | GAA (0.67) | PTGESKDM4EALDH1A1GAAMAPT | |
| SCHEMBL4794657 | 0.81 | PTGES (0.69) | PTGESKDM4EALDH1A1GAAMAPT | |
| SCHEMBL4052603 | 0.80 | PTGES (0.67) | PTGESKDM4EALDH1A1GAAMAPT | |
| SCHEMBL20211621 | 0.80 | KDM4E (1.00) | PTGESKDM4EALDH1A1GAAMAPT | |
| SCHEMBL30516133 | 0.80 | KDM4E (1.00) | PTGESKDM4EALDH1A1GAAMAPT | |
| SCHEMBL2951791 | 0.78 | PTGES (0.63) | PTGESKDM4EALDH1A1GAAMAPT | |
| SCHEMBL28252744 | 0.77 | NPC1 (0.55) | PTGESKDM4EALDH1A1GAAMAPT | |
| SCHEMBL16667971 | 0.77 | PTGES (0.62) | PTGESKDM4EALDH1A1GAAMAPT | |
| SCHEMBL30373338 | 0.77 | PTGES (0.62) | PTGESKDM4EALDH1A1GAAMAPT | |
| SCHEMBL16675555 | 0.77 | PTGES (0.62) | PTGESKDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111440201-B | Preparation method and application of organic compound | 齐齐哈尔大学 | 2022-06-21 | — | — | CN | claimed |
| CN-111440201-A | Preparation method and application of organic compound | 齐齐哈尔大学 | 2020-07-24 | — | — | CN | claimed |
| CN-111440201-B | Preparation method and application of organic compound | 齐齐哈尔大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-111440201-A | Preparation method and application of organic compound | 齐齐哈尔大学 | 2020-07-24 | — | — | CN | disclosed |