Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | TDO2 | P48775 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30373338 | 1.00 | PTGES (0.62) | PTGESMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16667971 | 1.00 | PTGES (0.62) | PTGESMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2951161 | 0.94 | ALDH1A1 (0.60) | PTGESMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29829906 | 0.94 | ALDH1A1 (0.60) | PTGESMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13007531 | 0.91 | PTGES (0.54) | PTGESMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29861634 | 0.91 | PTGES (0.55) | PTGESMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL762462 | 0.91 | PTGES (0.54) | PTGESMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29065756 | 0.91 | GAA (0.62) | PTGESMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14023475 | 0.91 | MEN1 (0.57) | PTGESMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28049482 | 0.91 | PTGES (0.62) | PTGESMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9452989-B2 | Compounds, sensors, methods, and systems for detecting gamma radiation | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-09-27 | — | — | US | disclosed |
| US-9452989-B2 | Compounds, sensors, methods, and systems for detecting gamma radiation | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-09-27 | — | — | US | disclosed |
| US-20150118758-A1 | COMPOUNDS, SENSORS, METHODS, AND SYSTEMS FOR DETECTING GAMMA RADIATION | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2015-04-30 | — | — | US | disclosed |
| US-20150118758-A1 | COMPOUNDS, SENSORS, METHODS, AND SYSTEMS FOR DETECTING GAMMA RADIATION | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150118758-A1 | COMPOUNDS, SENSORS, METHODS, AND SYSTEMS FOR DETECTING GAMMA RADIATION | RAD50, MRE11, IRF3 | PTGES 2304/4885MEN1 365/4885KMT2A 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.