Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743650 | 0.84 | SLC6A3 (0.43) | SLC6A3KDM4EPKM | |
| SCHEMBL28036657 | 0.81 | SLC6A3 (0.35) | SLC6A3 | |
| SCHEMBL28036227 | 0.80 | SLC6A3 (0.34) | SLC6A3KDM4EPKM | |
| SCHEMBL9051451 | 0.79 | KDM4E (0.38) | SLC6A3MEN1LMNAMAPTKMT2A | |
| SCHEMBL28036653 | 0.79 | P2RX7 (0.35) | SLC6A3 | |
| SCHEMBL28036656 | 0.79 | SLC6A3 (0.36) | SLC6A3MAPT | |
| SCHEMBL28036225 | 0.79 | P2RX7 (0.35) | SLC6A3 | |
| SCHEMBL27764214 | 0.78 | SLC6A3 (0.33) | SLC6A3MEN1LMNAKMT2A | |
| SCHEMBL27741460 | 0.78 | LY96 (0.34) | SLC6A3KDM4EPKM | |
| SCHEMBL27743460 | 0.78 | SLC6A3 (0.33) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107151243-B | 2-substituted-4-methyl-5- (4, 5-dihydrothiazole-2-yl) -1, 3-thiazole compounds, preparation method and biological activity evaluation thereof | 江苏海洋大学 | 2020-09-08 | — | — | CN | disclosed |