SCHEMBL284539

SCHEMBL284539

CCCCCCCCCCCCn1ccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 12/20 1.00
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
QPCT Q16769 1/20 0.54
PRKCI P41743 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4067377 1.00 TBXAS1 (1.00) TBXAS1KDM4ELMNAQPCTPRKCI
SCHEMBL521865 1.00 TBXAS1 (1.00) TBXAS1KDM4ELMNAQPCTPRKCI
SCHEMBL4062530 1.00 TBXAS1 (1.00) TBXAS1KDM4ELMNAQPCTPRKCI
SCHEMBL413378 1.00 TBXAS1 (1.00) TBXAS1KDM4ELMNAQPCTPRKCI
SCHEMBL4059134 1.00 TBXAS1 (1.00) TBXAS1KDM4ELMNAQPCTPRKCI
SCHEMBL284386 1.00 TBXAS1 (1.00) TBXAS1KDM4ELMNAQPCTPRKCI
SCHEMBL411866 1.00 TBXAS1 (1.00) TBXAS1KDM4ELMNAQPCTPRKCI
SCHEMBL304926 1.00 TBXAS1 (1.00) TBXAS1KDM4ELMNAQPCTPRKCI
SCHEMBL4347825 1.00 TBXAS1 (1.00) TBXAS1KDM4ELMNAQPCTPRKCI
SCHEMBL1685378 1.00 TBXAS1 (1.00) TBXAS1KDM4ELMNAQPCTPRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192633-A Epoxy resin composition and preparation method thereof, electric insulating part and preparation method thereof 麦克奥迪(厦门)智能电气有限公司 2025-06-24 CN claimed
CN-120040468-A Functional polyion liquid composite material and preparation method and application thereof 中国科学院过程工程研究所 2025-05-27 CN claimed
US-20250115785-A1 SLURRY COMPOSITION FOR CHEMICAL MECHANICAL METAL POLISHING AND POLISHING METHOD USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-04-10 US claimed
CN-119615616-A Ionic liquid impregnated modified antibacterial nylon fiber and preparation method thereof 中国科学院过程工程研究所 2025-03-14 CN claimed
CN-119552711-A Cleaning solution and application thereof in alkaline phosphatase magnetic particle chemiluminescence 捷和泰(北京)生物科技有限公司 2025-03-04 CN claimed
CN-119505228-A Ionic liquid grafted modified high-temperature-resistant bio-based nylon and preparation method and application thereof 中国科学院过程工程研究所 2025-02-25 CN claimed
CN-119433749-A Preparation method and application of imidazole salt graphene modified nylon fiber 宿迁市康莱建设工程有限公司 2025-02-14 CN claimed
CN-119080278-B Oilfield produced water treatment agent and preparation method thereof 淄博正河净水剂有限公司 2025-01-10 CN claimed
US-20240409935-A1 Atg8ylation coordinates stress granule formation and mTOR inactivation in response to lysosomal damage UNM RAINFOREST INNOVATIONS (US) 2024-12-12 US claimed
CN-117777576-B High-wear-resistance rubber runway and preparation method thereof 天津纽威特橡胶制品股份有限公司 2024-04-30 CN claimed
US-5250194-A Slimicides, fungicides; for aqueous systems, cooling water, papermaking, paints BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1993-10-05 US claimed
EP-0349763-A1 Compositions for enhancing transdermal penetration Bristol-Myers Squibb Company (US) 1990-01-10 EP claimed
US-4885228-A ONE LAYER CONTAINING A CYANINE DYE; HEAT, MOISTURE AND LIGHT RESISTANCE; LASER BEAM READING FUJI PHOTO FILM CO., LTD. (JP) 1989-12-05 US claimed
US-4761181-A STABILIZING DYES WITH A DITHIOLATO METAL COMPLEX FUJI PHOTO FILM CO., LTD. (JP) 1988-08-02 US claimed
EP-0180263-A2 Method for controlling vascular withering diseases in plants, especially dutch elm disease Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO (NL) 1986-05-07 EP claimed
EP-0064803-B1 INSECTICIDAL COMPOSITIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-21 EP claimed
US-4532268-A Imidazole agent for retarding the polymerization of aziridine compounds ESPE, FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1985-07-30 US claimed
EP-0001809-B1 SYNERGETIC INSECTICIDAL AND ACARICIDAL MIXTURES BASF Aktiengesellschaft (DE) 1982-02-03 EP claimed
US-4194001-A MITICIDALF WITH N-DODECYLIMIDAZOLE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-03-18 US claimed
EP-0001809-A1 Synergetic insecticidal and acaricidal mixtures BASF Aktiengesellschaft (DE) 1979-05-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409935-A1 Atg8ylation coordinates stress granule formation and mTOR inactivation in response to lysosomal damage LAMTOR3, MLST8, ATG7 TBXAS1 2690/4885KDM4E 2387/4885LMNA 1802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.