Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28460402 | 0.84 | MAPT (0.40) | KDM4ESMN1; SMN2ALDH1A1MAPTTHRB | |
| SCHEMBL2815306 | 0.78 | HTT (0.39) | SMN1; SMN2ALDH1A1LMNAHTTMAPT | |
| SCHEMBL341369 | 0.68 | TDP1 (0.41) | KDM4ESMN1; SMN2ALDH1A1TP53LMNA | |
| SCHEMBL7389957 | 0.68 | MAPT (0.40) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL21769890 | 0.68 | HTT (0.36) | SMN1; SMN2ALDH1A1HTTMAPTTHRB | |
| SCHEMBL2815309 | 0.68 | HTT (0.39) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL28459274 | 0.67 | GAA (0.36) | KDM4EALDH1A1TP53LMNAHTT | |
| SCHEMBL2037132 | 0.65 | ALDH1A1 (0.51) | KDM4ESMN1; SMN2ALDH1A1MITFLMNA | |
| SCHEMBL11435633 | 0.64 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2ALDH1A1TP53LMNA | |
| SCHEMBL2773909 | 0.63 | CNR2 (0.45) | SMN1; SMN2ALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623577-B | Preparation method of amonebvir and intermediate thereof | 山东百诺医药股份有限公司 | 2020-09-25 | — | — | CN | disclosed |