Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | DDIT3 | P35638 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452446 | 0.88 | TDP1 (0.40) | TDP1KMT2AMEN1GAAGLA | |
| SCHEMBL28455352 | 0.80 | NPC1 (0.60) | KMT2AMEN1GAAGLAKDM4E | |
| SCHEMBL28449547 | 0.79 | ADCY1 (0.41) | TDP1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL22594348 | 0.69 | ADCY1 (0.53) | TDP1KDM4ELMNAHTTNPC1 | |
| SCHEMBL24290767 | 0.68 | KMT2A (0.78) | KMT2AMEN1GAAGLAKDM4E | |
| SCHEMBL7485465 | 0.67 | DDIT3 (0.53) | TDP1KMT2AMEN1GAAGLA | |
| SCHEMBL18952982 | 0.67 | TDP1 (0.69) | TDP1KMT2AMEN1GAAGLA | |
| SCHEMBL6432446 | 0.67 | MITF (0.68) | TDP1KMT2AMEN1DDIT3L3MBTL1 | |
| SCHEMBL1899946 | 0.66 | STAT3 (0.64) | TDP1KMT2AMEN1GAAGLA | |
| SCHEMBL7485300 | 0.66 | DDIT3 (0.52) | KMT2AMEN1GAAGLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535146-B | Antituberculous compound and its preparation method and use | 中国医学科学院医药生物技术研究所 | 2020-09-22 | — | — | CN | disclosed |