Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28454450 | 0.80 | TDP1 (0.49) | NPC1RAB9APOLBMAPTGAA | |
| SCHEMBL7485465 | 0.78 | DDIT3 (0.53) | NPC1RAB9APOLBSMN1; SMN2GAA | |
| SCHEMBL7485300 | 0.76 | DDIT3 (0.52) | NPC1RAB9APOLBSMN1; SMN2GAA | |
| SCHEMBL4468305 | 0.72 | ALDH1A1 (0.68) | NPC1RAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL7486429 | 0.71 | DDIT3 (0.47) | NPC1RAB9APOLBSMN1; SMN2GAA | |
| SCHEMBL28452446 | 0.71 | TDP1 (0.40) | NPC1RAB9APOLBGAAL3MBTL1 | |
| SCHEMBL7482315 | 0.71 | RAB9A (0.50) | NPC1RAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL7483947 | 0.70 | RAB9A (0.52) | NPC1RAB9APOLBMAPTGAA | |
| SCHEMBL16919100 | 0.70 | ALDH1A1 (0.58) | NPC1RAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL7484123 | 0.69 | KMT2A (0.55) | NPC1RAB9APOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535146-B | Antituberculous compound and its preparation method and use | 中国医学科学院医药生物技术研究所 | 2020-09-22 | — | — | CN | claimed |
| CN-109535146-B | Antituberculous compound and its preparation method and use | 中国医学科学院医药生物技术研究所 | 2020-09-22 | — | — | CN | disclosed |