Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390169 | 0.83 | ESR1 (0.40) | ALDH1A1MAPTTSHRKMT2AL3MBTL1 | |
| SCHEMBL7428081 | 0.79 | ESR2 (0.45) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL15188909 | 0.79 | KMT2A (0.38) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL4062712 | 0.79 | CES2 (0.41) | GSK3BALDH1A1TSHRKMT2AL3MBTL1 | |
| SCHEMBL12968160 | 0.77 | L3MBTL1 (0.36) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL27572839 | 0.77 | TDP1 (0.36) | GSK3BALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL7420669 | 0.76 | GSK3B (0.40) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL27397367 | 0.74 | GSK3B (0.41) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL25546046 | 0.73 | ESR1 (0.44) | F2PLGPLAUKLKB1PRSS1 | |
| SCHEMBL12958709 | 0.70 | GSK3B (0.35) | F2PLGPLAUKLKB1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635523-A | Two-dimensional covalent organic framework material with trimeric quinazoline as junction, preparation method and application thereof | 河北科技大学 | 2020-09-08 | — | — | CN | claimed |
| CN-111635523-A | Two-dimensional covalent organic framework material with trimeric quinazoline as junction, preparation method and application thereof | 河北科技大学 | 2020-09-08 | — | — | CN | disclosed |