Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420669 | 0.89 | GSK3B (0.40) | GSK3BL3MBTL1F2PLGPLAU | |
| SCHEMBL12968160 | 0.85 | L3MBTL1 (0.36) | GSK3BL3MBTL1F2PLGPLAU | |
| SCHEMBL15188909 | 0.76 | KMT2A (0.38) | GSK3BL3MBTL1F2PLGPLAU | |
| SCHEMBL7428081 | 0.76 | ESR2 (0.45) | GSK3BL3MBTL1F2PLGPLAU | |
| SCHEMBL28454906 | 0.74 | F2 (0.38) | GSK3BL3MBTL1F2PLGPLAU | |
| SCHEMBL27572839 | 0.73 | TDP1 (0.36) | GSK3BL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27525400 | 0.73 | TDP1 (0.36) | GSK3BL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12958709 | 0.69 | GSK3B (0.35) | GSK3BL3MBTL1F2PLGPLAU | |
| SCHEMBL7929205 | 0.69 | USP28 (0.34) | L3MBTL1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL27455430 | 0.68 | GSK3B (0.39) | GSK3BKMT2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093856-C | Substituted sulfonic acid N- [ (aminoiminomethyl) phenylalkyl ] -azacyclic amide compounds | AVENTIS PHARM PROD INC (US) | 2002-11-06 | — | — | CN | disclosed |
| CN-1190395-A | Substituted (sulfonic, sulfinic, sulfonamido or sulfonamido) N- [ aminoiminomethyl) phenylalkyl ] -azaheterocyclic amide compounds | RHONE POULENC RORER PHARMA (US) | 1998-08-12 | — | — | CN | disclosed |