Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | ALPG | P10696 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13263679 | 0.81 | ALPG (0.49) | FPR2KDM4EALDH1A1HDAC6ALPG | |
| SCHEMBL16607258 | 0.77 | FPR2 (0.43) | FPR2ALPGPLAAALPL | |
| SCHEMBL11930749 | 0.76 | FPR2 (0.42) | FPR2KDM4EALDH1A1HDAC6ALPG | |
| SCHEMBL23975326 | 0.75 | FPR2 (0.41) | FPR2KDM4EALDH1A1HDAC6ALPG | |
| SCHEMBL21539580 | 0.75 | FPR2 (0.41) | FPR2KDM4EALDH1A1HDAC6ALPG | |
| SCHEMBL15335292 | 0.75 | ALPL (0.47) | FPR2KDM4EALDH1A1HDAC6ALPG | |
| SCHEMBL18079522 | 0.74 | FPR2 (0.37) | FPR2KDM4EALDH1A1HDAC6ALPG | |
| SCHEMBL10553435 | 0.74 | FPR2 (0.51) | FPR2KDM4EALDH1A1HDAC6CA12 | |
| SCHEMBL10916148 | 0.74 | FPR2 (0.46) | FPR2KDM4EALDH1A1HDAC6OPRD1 | |
| SCHEMBL13233404 | 0.74 | FPR2 (0.46) | FPR2KDM4EALDH1A1HDAC6OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146196-A | FAP inhibitors | 海德堡大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-111699181-A | FAP inhibitors | 海德堡大学 | 2020-09-22 | — | — | CN | disclosed |