Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | PDE2A | O00408 | 1/20 | 0.56 |
| ▸ | PKLR | P30613 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792486 | 0.83 | HSD17B3 (0.73) | HSD17B3NPSR1RXFP1PDE2APKLR | |
| SCHEMBL28383872 | 0.81 | HSD17B3 (0.73) | HSD17B3NPSR1RXFP1PDE2APKLR | |
| SCHEMBL8848474 | 0.79 | HSD17B3 (0.77) | HSD17B3NPSR1RXFP1PDE2APKLR | |
| SCHEMBL5273182 | 0.78 | CA9 (0.53) | NPSR1RXFP1KDM4EALDH1A1GLA | |
| SCHEMBL16435351 | 0.76 | ERAP1 (0.64) | HSD17B3NPSR1RXFP1PDE2AKDM4E | |
| SCHEMBL2195842 | 0.76 | ALDH1A1 (0.68) | NPSR1KDM4EALDH1A1ESR1GLA | |
| SCHEMBL29493311 | 0.76 | ALDH1A1 (0.68) | NPSR1KDM4EALDH1A1ESR1GLA | |
| SCHEMBL16663940 | 0.75 | PDE2A (0.85) | HSD17B3NPSR1RXFP1PDE2APKLR | |
| SCHEMBL1024770 | 0.75 | HSD17B3 (1.00) | HSD17B3NPSR1PDE2AKDM4EALDH1A1 | |
| SCHEMBL30640528 | 0.75 | HSD17B3 (1.00) | HSD17B3NPSR1PDE2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499604-B | Lysosome targeted Cys near-infrared fluorescent probe and preparation method and application thereof | 山西大学 | 2022-03-18 | — | — | CN | claimed |
| CN-111499604-A | Lysosome targeted Cys near-infrared fluorescent probe and preparation method and application thereof | 山西大学 | 2020-08-07 | — | — | CN | claimed |
| CN-111499604-B | Lysosome targeted Cys near-infrared fluorescent probe and preparation method and application thereof | 山西大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-111499604-A | Lysosome targeted Cys near-infrared fluorescent probe and preparation method and application thereof | 山西大学 | 2020-08-07 | — | — | CN | disclosed |