Sugi Predict

Sugi Predict / Compounds / SCHEMBL5273182

SCHEMBL5273182

SCHEMBL5273182

O=Cc1c(Cl)c2ccccc2oc1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA9 Q16790 6/20 0.53
▸ CA2 P00918 5/20 0.53
▸ KDM4E B2RXH2 5/20 0.51
▸ THRB P10828 1/20 0.51
▸ ALDH1A1 P00352 4/20 0.47
▸ MAPT P10636 3/20 0.47
▸ LMNA P02545 3/20 0.47
▸ NPSR1 Q6W5P4 3/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ HSD17B10 Q99714 2/20 0.47
▸ GMNN O75496 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ ELANE P08246 1/20 0.47
▸ CTSG P08311 1/20 0.47
▸ CTSA P10619 1/20 0.47
▸ CYP2D6 P10635 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15842324 0.83 KDM4E (0.56) CA9KDM4ETHRBALDH1A1MAPT
SCHEMBL29952602 0.79 NQO1 (0.49) CA9CA2ALDH1A1MAOAADORA3
SCHEMBL2540914 0.79 ALDH1A1 (0.53) CA9CA2KDM4EALDH1A1MAPT
SCHEMBL13417538 0.79 KDM4E (0.54) CA9KDM4ETHRBALDH1A1MAPT
SCHEMBL2232638 0.79 KDM4E (0.59) CA9KDM4EALDH1A1MAPTLMNA
SCHEMBL27799769 0.79 GAA (0.65) KDM4ETHRBALDH1A1MAPTLMNA
SCHEMBL28455437 0.78 HSD17B3 (0.60) CA9KDM4ETHRBALDH1A1MAPT
SCHEMBL3196866 0.77 CA2 (0.57) CA9CA2KDM4EALDH1A1MAPT
SCHEMBL9910631 0.77 CA9 (0.48) CA9CA2MAOACA12
SCHEMBL17845026 0.77 MEN1 (0.56) CA9CA2KDM4ELMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12422443-B2 Amino-substituted chromenoquinoline-based fluorescent marker, and preparation and use thereof SOOCHOW UNIVERSITY (CN) 2025-09-23 — — US claimed
US-20240353433-A1 AMINO-SUBSTITUTED CHROMENOQUINOLINE-BASED FLUORESCENT MARKER, AND PREPARATION AND USE THEREOF SOOCHOW UNIVERSITY (CN) 2024-10-24 — — US claimed
WO-2023092814-A1 AMINO-SUBSTITUTED CHROMENOQUINOLINE TYPE FLUORESCENT MARKER, AND PREPARATION AND USE THEREOF 苏州大学 2023-06-01 — — WO claimed
CN-114149441-B Amino-substituted chromene quinoline fluorescent marker and preparation and application thereof 苏州大学 2022-12-30 — — CN claimed
CN-114149441-A Amino-substituted chromene quinoline fluorescent marker and preparation and application thereof 苏州大学 2022-03-08 — — CN claimed
CN-121850990-A Cadmium ion fluorescent probe and synthetic method and application thereof 山东第一医科大学第一附属医院(山东省千佛山医院) 2026-04-14 — — CN disclosed
US-12422443-B2 Amino-substituted chromenoquinoline-based fluorescent marker, and preparation and use thereof SOOCHOW UNIVERSITY (CN) 2025-09-23 — — US disclosed
US-20240353433-A1 AMINO-SUBSTITUTED CHROMENOQUINOLINE-BASED FLUORESCENT MARKER, AND PREPARATION AND USE THEREOF SOOCHOW UNIVERSITY (CN) 2024-10-24 — — US disclosed
CN-114773334-B Indolo [2, 1-alpha ] isoquinoline compound and preparation method and application thereof 杭州医学院 2023-09-19 — — CN disclosed
WO-2023092814-A1 AMINO-SUBSTITUTED CHROMENOQUINOLINE TYPE FLUORESCENT MARKER, AND PREPARATION AND USE THEREOF 苏州大学 2023-06-01 — — WO disclosed
CN-114149441-B Amino-substituted chromene quinoline fluorescent marker and preparation and application thereof 苏州大学 2022-12-30 — — CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 — — US disclosed
US-7671069-B2 Tricyclic, heteroaromatic compounds modulating CXCR4 and/ or CXCR7 CHEMOCENTRYX, INC. (US) 2010-03-02 — — US disclosed
WO-2007133211-A1 3,4-DISUBSTITUTED COUMARIN AND QUINOLONE COMPOUNDS XTL BIOPHARMACEUTICALS, LTD. (IL) 2007-11-22 — — WO disclosed
EP-1853257-A2 PYRAZOLE COMPOUNDS Vivoquest, Inc. (US) 2007-11-14 — — EP disclosed
US-20070254915-A1 CXCR4 MODULATORS CHEMOCENTRYX, INC. (US) 2007-11-01 — — US disclosed
US-20070254915-A1 CXCR4 MODULATORS CHEMOCENTRYX, INC. (US) 2007-11-01 — — US disclosed
WO-2007115232-A2 CXCR4 MODULATORS CHEMOCENTRYX, INC. (US) 2007-10-11 — — WO disclosed
WO-2006088903-A2 PYRAZOLE COMPOUNDS VIVOQUEST, INC. (US) 2006-08-24 — — WO disclosed
US-20060183751-A1 Pyrazole compounds PRESIDIO PHARMACEUTICALS, INC. 2006-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060183751-A1 Pyrazole compounds MAVS, EIF2AK2, ZC3HAV1 CA9 4746/4885CA2 4879/4885KDM4E 2663/4885
US-20070254915-A1 CXCR4 MODULATORS CXCL12, CXCR4, CXCR1 CA9 1386/4885CA2 1616/4885KDM4E 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.