Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28450973 | 1.00 | MAOA (0.67) | MAOAPGRPSMD14MEN1MAPT | |
| SCHEMBL28440902 | 0.94 | PSMD14 (0.61) | MAOAPSMD14MEN1MAPTKMT2A | |
| SCHEMBL23052579 | 0.89 | MEN1 (0.60) | MAOAPSMD14MEN1MAPTKMT2A | |
| SCHEMBL30434230 | 0.88 | MAOA (0.55) | MAOAPGRPSMD14MEN1MAPT | |
| SCHEMBL28446516 | 0.88 | MAOA (0.55) | MAOAPGRPSMD14MEN1MAPT | |
| SCHEMBL28440914 | 0.87 | MEN1 (0.70) | MAOAPSMD14MEN1MAPTKMT2A | |
| SCHEMBL28897908 | 0.83 | KMT2A (0.65) | PGRMEN1MAPTKMT2AHTT | |
| SCHEMBL23052580 | 0.83 | PSMD14 (0.61) | MAOAPGRPSMD14MEN1MAPT | |
| SCHEMBL3316143 | 0.83 | MAOA (0.69) | MAOAPGRPSMD14MEN1MAPT | |
| SCHEMBL30435684 | 0.82 | MAPT (0.76) | MAOAMEN1MAPTKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423374-B | Dihydropyrazole sulfonamide compound and preparation method and application thereof | 合肥工业大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-111423374-A | Dihydropyrazole sulfonamide compound and preparation method and application thereof | 合肥工业大学 | 2020-07-17 | — | — | CN | disclosed |