SCHEMBL28457016

SCHEMBL28457016

[c]1ccc(-c2[nH]cc3ccccc23)cc1

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP2A6 P11509 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PARP1 P09874 1/20 0.31
MAPK1 P28482 2/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
IMPDH2 P12268 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL774738 0.84 ESR1 (0.42) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL1672648 0.79 ALDH1A1 (0.43) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL13183725 0.77 RAB9A (0.42) HSD17B10ALDH1A1TDP1PARP1MAPK1
SCHEMBL21917644 0.73 KDM4E (0.47) ALDH1A1TDP1PARP1KDM4EMAPT
SCHEMBL13183867 0.73 TNKS (0.43) PARP1
SCHEMBL10967133 0.72 ALDH1A1 (0.30) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL30068451 0.70 CYP11B1 (0.53) HSD17B10ALDH1A1CYP2A6KDM4EMAPT
SCHEMBL13183740 0.69 NPC1 (0.41) ALDH1A1CYP2A6TSHRMAPK1KDM4E
SCHEMBL647671 0.68 NISCH (0.40) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL16796324 0.68 CYP3A4 (0.39) ALDH1A1CYP2A6TDP1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111662334-A Organometallic compound, organic light emitting device, and apparatus including organic light emitting device 三星显示有限公司 2020-09-15 CN disclosed